Christian Braendle, Ph.D.
Biologie
Université de Nice Sophia-Antipolis
Born in 1973 in Solothurn, Switzerland
Studied Biology at the University of Basel, at Princeton University, and at the University of Cambridge
Schwerpunkt
Adaptive PlastizitätArbeitsvorhaben
Abschätzung der Bedeutung von genetischer und phänotypischer Anpassung im Evolutionsprozess
Phenotypic plasticity describes any form of environmentally induced phenotypic variation and is a common feature of most organismal traits. Central in the nature-nurture debate, phenotypic plasticity reflects the flexibility of a single genome to express a variety of different phenotypes. Phenotypic plasticity is now an intensively studied phenomenon in diverse biological disciplines, but it is evolutionary biologists in particular who have embraced this concept to address a wide range of questions: How does environmental variation shape the evolution of plastic responses? Which aspects of phenotypic plasticity are adaptive? Which mechanisms underlie particular examples of adaptive plasticity? Does plasticity incur costs? What is the impact of phenotypic plasticity in the evolutionary process? Much debate revolves around the latter question, i.e. how phenotypic plasticity influences fundamental evolutionary processes, such as rates of diversification and speciation. During my participation in the focus group on Adaptive Plasticity, I propose to re-examine relevant major concepts (genetic and phenotypic accommodation, genetic assimilation) and clarify their definitions, critically analyze empirical evidence put forward in support of these phenomena, and finally, outline promising experimental approaches to explicitly test whether and how plasticity impacts phenotypic evolution.Recommended Reading
Braendle, C., C. Baer und M. A. Félix (2010). "Bias and evolution of the mutationally accessible phenotypic space in a developmental system." PLoS Genetics, e1000877.
Braendle, C. and M. A. Félix (2008). "Plasticity and errors of a robust developmental system in different environments." Developmental Cell 15: 714-724.
Braendle, C. and T. Flatt (2006). "A role for genetic accommodation in evolution?" BioEssays 28: 868-873.
Publikationen aus der Fellowbibliothek
Braendle, Christian (2011)
Integrating mechanistic and evolutionary analysis of life history variation
Braendle, Christian (2010)
The natural history of Caenorhabditis elegans
Braendle, Christian (2010)
Bias and evolution of the mutationally accessible phenotypic space in a developmental system
Braendle, Christian (2009)
Braendle, Christian (2008)
Mechanisms and evolution of environmental responses in Caenorhabditis elegans
Braendle, Christian (Cambridge, Mass., 2008)
Plasticity and errors of a robust developmental system in different environments
Braendle, Christian (2006)
Braendle, Christian (2006)
Sex determination : ways to evolve a hermaphrodite
Braendle, Christian (2006)
A role for genetic accommodation in evolution?
Braendle, Christian (2005)
